The CD63 gene is located on human chromosome 12q13 and is the first characterized tetraspanin. Originally, CD63 was discovered as a protein present on the cell surface of activated blood platelets, known as platelet glycoprotein 40 and in early stage human melanoma cells, where it was known as melanoma antigen 491.
https://www.creative-biolabs.com/adc/development-of-cd63-based-bispecific-adcs.htm
The CD63 gene is located on human chromosome 12q13 and is the first characterized tetraspanin. Originally, CD63 was discovered as a protein present on the cell surface of activated blood platelets, known as platelet glycoprotein 40 and in early stage human melanoma cells, where it was known as melanoma antigen 491.